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Cardiovascular Drugs
Chlorthalidone
Rx or OTC: Rx
Dosage: 12.5-50 mg daily
Route: Oral
Pregnancy Category: B
DEA Schedule: Not controlled
Pronunciation: klor-THAL-i-doan
Nifedipine
Drug Classifications: Thiazide-like diuretic
Common Prefixes/Suffixes: -thiazide (thiazide-like diuretics)
Mechanism of Action: Inhibits sodium reabsorption, edema
promoting diuresis.
Indications: Hypertension, edema
Contraindications: Anuria, sulfa allergy
Side Effects: Hypokalemia, hyperkalemia, hypergycemia
Drug Interactions: Lithium, digoxin, NSAIDs
Nursing Implications: Monitor electrolytes, BP, and glucose levels.
Sitagliptin
Endocrine Drugs
Hydrocortisone
Endocrine Drugs
Rx or OTC: Rx
Dosage: Varies (e.g. 10 mg, 20 mg, 100 mg)
Route: Oral, Topical, IV
Pregnancy Category: C
DEA Schedule: Not controlled
Musculoskeletal Drugs
Zolpidem
Drug Classifications: Antigout agent
Common Prefixes/Suffixes: -purinol (antigout agents)
Mechanism of Action: Inhibits xanthine oxidase,
reducing uric acid production.
Indications: Gout, hyperuricemia
Contraindications: Hypersensitivity to allopurinol,
Syndrome
Side Effects: Rash, hypertoxicity, Stevens-Johnson
Drug Interactions: Azathioprine, warfarin
Nursing Implications: Monitor for rash and liver
function; increase fluid intake.
Immunologic Drugs
Drug Classifications: T-cell Co-stimulation Modulator
Common Prefixes/Suffixes: -cept (fusion proteins)
Mechanism of Action: Inhibits T-cell activation by
binding to CD80/CD86 on antigen-presenting cells.
Indications: Rheumatoid arthritis, juvenile idiopathic
arthritis
Contraindications: Hypersensitivity to abatac
er
Side Effects: Infections, headache, TNF inhibitors
Drug Interactions: Live vaccines, monitor for signs of
infection.
Nursing Implications: Avoid live vaccines during therapy.
Pain and Inflammation Drugs
Indomethacin
Drug Classifications: Muscle Relaxant
Common Prefixes/Suffixes: None
Mechanism of Action: Reduces muscle spasms by acting
on the brainstem.
Indications: Muscle spasms, acute musculoskeletal pain
Contraindications: Drowsiness, dry mouth, hyperthyroidism
Side Effects: MAOI use, hyperthyroidism, dizziness
Drug Interactions: CNS depressants, beta-blockers, ACE
inhibitors
Nursing Implications: Monitor for sedation, educate
about alcohol and CNS depressants.
Hematologic Drugs
Defibrotide
Drug Classifications: Monoclonal Antibody
Common Prefixes/Suffixes: -mab (monoclonal antibodies)
Mechanism of Action: Reverses the anticoagulant effect
of dabigatran by binding to it.
Indications: Reversal of dabigatran in emergency
situations
Contraindications: None known
Side Effects: Hypersensitivity, thromboembolic events
Drug Interactions: None significant
Nursing Implications: Administer in a controlled set-
ting; monitor for bleeding and thrombosis.
Psychiatric Drugs
Drug Classifications: Mood Stabilizer
Common Prefixes/Suffixes: None
Mechanism of Action: Modulates neurotransmitter activity,
stabilizes mood.
Indications: Bipolar Disorder
Contraindications: Severe renal or cardiac disease
Side Effects: Tremor, polyuria, hypothyroidism
Drug Interactions: MAO inhibitors, diuretics, NSAIDs, ACE
inhibitors
Nursing Implications: Monitor serum lithium levels, ed-
ucate on hydration.
Renal/Urologic Drugs
Sevelamer
Drug Classifications: Anticholinergic
Common Prefixes/Suffixes: -fenacin (anticholinergics)
Mechanism of Action: Blocks muscarinic receptors, reducing
bladder overactivity.
Indications: Overactive bladder (OAB)
Contraindications: Urinary retention, constipation, gastric
retention,
uncontrolled narrow-angle glaucoma
Side Effects: Dry mouth, constipation, blurred vision
Drug Interactions: Other anticholinergics, CYP3A4 inhibitors
Nursing Implications: Monitor for anticholinergic effects,
avoid opioid use.
Dermatologic Drugs
Drug Classifications: Retinoid
Common Prefixes/Suffixes: -lene (retinoids)
Mechanism of Action: Normalizes keratinization.
Indications: Acne
Contraindications: Dryness, redness, irritation
Side Effects: Hypersensitivity, irritation
Drug Interactions: None significant
Nursing Implications: Avoid sunlight
exposure; use sunscreen.
Gastrointestinal Drugs
Bisacodyl
Rx or OTC: OTC
Dosage: 5 mg (tablets or suppositories)
Route: Oral, rectal
Pregnancy Category: C
DEA Schedule: Not controlled
Pronunciation: bis-AK-oh-dih
Drug Classifications: Stimulant laxative
Common Prefixes/Suffixes: -dyl (stimulant laxatives)
Mechanism of Action: Stimulates bowel movements by
increasing peristalsis and water secretion.
Indications: Constipation, bowel preparation for procedures
Contraindications: Intestinal obstruction, diarrhea, electrolyte
imbalances
Side Effects: Abdominal cramping, diarrhea, reduced efficacy
Drug Interactions: Antacids (reduce absorption), warfar
in
Nursing Implications: Administer on an empty stomach;
avoid long-term use.
Respiratory Drugs
Mometasone
Drug Classifications: Long-acting Beta-2 Agonist (LABA)
Common Prefixes/Suffixes: -terol (beta-2 agonists)
Mechanism of Action: Stimulates beta-2 adrenergic
receptors, causing prolonged bronchodilation.
Indications: Asthma, COPD
Contraindications: Acute asthma attack, tremors, nervousness
Side Effects: Tachycardia, headache, TNF inhibitors
Drug Interactions: Beta-blockers, other
sympathomimetics
Nursing Implications: Not for acute bronchospasm;
with ICS for asthma.
Neurological Drugs
Drug Classifications: Adrenergic agonist, Vasopressor
Common Prefixes/Suffixes: -amine (biogenic amines)
Mechanism of Action: Stimulates dopamine receptors,
increases heart rate and blood pressure.
Indications: Shock, heart failure, hypotension
Contraindications: Tachycardia, hypertension, arrhythmias
filbrillation
Side Effects: MAO inhibitors, beta-blockers, heart
Drug Interactions: Monitor blood pressure, heart
rate, and ECG; titrate dose carefully.
Infectious Disease Drugs
Azithromycin
Rx or OTC: Rx
Dosage: 500 mg once daily for 3 days
Route: Oral, IV
Pregnancy Category: B
DEA Schedule: Not controlled
Pronunciation: ay-ZITH-roh-my-sin
Drug Classifications: Macrolide antibiotic
Common Prefixes/Suffixes: -thromycin (macrolide class)
Mechanism of Action: Inhibits bacterial protein synthesis by
binding to the 50S ribosomal subunits.
Indications: Respiratory infections, skin infections, sexually
transmitted infections (e.g., chlamydia).
Contraindications: Hypersensitivity to macrolides, QT
prolongation.
Side Effects: Abdominal pain, diarrhea, reduced absorption,
cholestatic jaundice.
Drug Interactions: Antacids (reduce absorption), warfar
in
(increases bleeding risk)
Nursing Implications: Monitor for care of patients with
prolongation.
Emergency Drugs
Naloxone
Rx or OTC: Rx/OTC (nasal spray)
Dosage: 0.4-2 mg (IV/IM, SubQ, Nasal)
Route: IV, IM, SubQ, Nasal
Pregnancy Category: B
DEA Schedule: Not controlled
Pronunciation: nal-OX-oh-n
Drug Classifications: Opioid Antagonist
Common Prefixes/Suffixes: -oxone (opioid antagonists)
Mechanism of Action: Competitively binds to opioid
receptors, reversing opioid effects.
Indications: Opioid overdose, respiratory depression
Contraindications: None in emergencies
Side Effects: Withdrawal symptoms, tachycardia, nausea,
hypertension
Drug Interactions: Opioids
Nursing Implications: Monitor respiratory rate,
prepare for withdrawal symptoms.
Oncology Drugs
Cyclophosphamide
Drug Classifications: Antineoplastic, Antimetabolite
Common Prefixes/Suffixes: -racil (antimetabolites)
Mechanism of Action: Inhibits thymidylate synthase,
disrupting DNA and RNA synthesis.
Indications: Breast cancer, skin cancer,
Colorectal cancer, B-cell lymphoma.
Contraindications: Dihydropyrimidine dehydrogenase
deficiency, myelosuppression, mucositis, diarrhea.
Side Effects: Leucovorin (enhances toxicity), other
hand-foot syndrome.
Drug Interactions: Monitor for mucositis and diarrhea,
Educate on hand-foot syndrome.