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"Everything looks normal, take a PPI" is not a plan. Here is why. A PPI does one thing: it lowers stomach acid. It does not improve motility, so if your stomach is emptying slowly and pressure is building under the LES, the reflux keeps happening. It is just less acidic. And a normal endoscopy does not mean no reflux. A standard scope looks at your esophagus and stomach. It does not look at your larynx, which is where LPR (silent reflux) does its damage. Throat clearing, hoarseness, a lump feeling, post-nasal drip. All real, all invisible on that scope. For LPR specifically, the problem is pepsin, the stomach enzyme that rides up with refluxate and damages throat tissue even when the reflux is not acidic. Lowering acid does not remove it. In the largest placebo-controlled PPI trial for reflux-related throat symptoms, 14.7% of patients on esomeprazole resolved vs 16.0% on placebo after 16 weeks. Vaezi et al. 2006, Laryngoscope, RCT, n=145, PMID 16467715. You were never doing it wrong. You were treating the wrong mechanism. Head to the link in my bio for loads of free resources. #refluxtok #silentreflux #LPR #acidreflux #guttok