What's worse: taking Calculus in college without taking it in high school, taking Physics in college without taking it in high school, or taking Chemistry in college without taking it in high school?

Well, I did all three, so I think I can give my opinion. I will rank them from, I guess, best to worst. Calc 1 was definitely the easiest class to take without having any exposure from high school. If you know basic algebra, you know the unit circle, and you can know the alphabet because you need to know what variables are for the quotient rule and product rule and so on and so forth, you're literally going to get a B in the class, like at minimum, if not an A. It's not that hard of a class. There's a lot of fear-mongering when it comes to the word calculus. It's a word that you hear thrown around, at least in the US, ever since you're in elementary school. Oh, calculus. But Calc 1 is not that bad. It only gets maybe a little bit more difficult towards the end when you learn some integration and it's leading you into Calc 2, but honestly, it's really not that hard of a course, at least from my experience, because my professor was good. Next up is Physics 1. This class was definitely very difficult. It was a lot harder than Calc 1 because it was subjective. It wasn't as simple as just memorizing the steps and just repeating the steps in every single problem on the exam. You actually have to know what you're doing, and my professor also wasn't that good. But there were a couple of students in there that did not take Physics in high school, just like I did, so I tried to relate to them a lot and tried to, I guess, work through it with them. It wasn't just everyone in there had taken it. But Chemistry was the worst because everybody takes Chemistry in high school and I didn't. The reason why I didn't was because my high school, a lot of students failed Chemistry. The teacher really sucked. It was so bad to where we took a different class called like Technical Physical Science or something where basically we learned like electron configuration and, you know, the periodic table, but we didn't learn stoichiometry, PV equals NRT, ice tables, like so on and so forth, like real chemistry. And when I went into college, I almost had no exposure to it. I basically just have seen the periodic table and I took that class in my junior year of high school, so it had been almost two years since I had even looked at the periodic table. That was by far the worst because every single student in there had already taken Chemistry and I took Chem for Engineers, which is a combination of Chem 101 and 102, and it was really, really accelerated and it was just an awful experience. But if you work through it, you'll be fine. I got an A in Calc 1, I got a B in Physics 1, I got a B in Chemistry for Engineers, because I put in the work.